Faridani Lab


Precision oncology

 Single-cell technology

 Cancer liquid biopsy








Our lab is focused on molecular biology, single-cell sequencing technologies and liquid biopsy in cancer. In particular, we are interested in pancreatic cancer diagnosis and treatment. 

The lab is located at two sites: Lowy Cancer Research Centre (at University of New South Wales, UNSW) and Garvan Institute of Medical Research in Sydney, Australia.  We are also affiliated to the Karolinska Institute in Stockholm, Sweden. We have access to cutting-edge instruments and facilities at UNSW and Garvan including next-generation sequencing, long-read sequencing (Nanopore Oxford Technology and PacBio), FACS, liquid handling robotics, automated micromanipulator, microfluidics, 3D printing, and microscopy. We collaborate closely with The Kinghorn Cancer Centre, The Ramaciotti Centre for Genomics, and Kinghorn Centre for Clinical Genomics.








About


We are interested in single-cell analysis to characterise the diversity of cell types in the human body. Studying a tissue in a single-cell resolution provides a more precise picture of its behaviour in health and disease. 

We are also studying  circulating tumour cells (CTCs), a diverse cell population that is released by solid tumours into the circulation in the form of single cells or cell clusters. CTCs can be used as a liquid biopsy to obtain information from tumours in a minimally invasive way. Our lab aims to investigate CTCs with single-cell technology to test whether they can potentially serve as a predictive/prognostic biomarker in solid cancers. 

To reach these aims, we use the latest technology and when there is none, we develop it.










Research






Open positions

PhD position in precision oncology, and single-cell sequencing technology , please contact o.faridani@unsw.edu.au


We are always looking for enthusiastic and brilliant students and postdocs who care about science and improving cancer patients' lives. Please send us your CV if you are interested in joining us.

Honour students and clinical students interested in doing a PhD in single cell technology, precision medicine, molecular biology and pancreatic cancer are encouraged to contact us. 




Publications and Patents

Selected publications

Faridani OR, Abdullayev I, Hagemann-Jensen M, Schell JP, Lanner F, Sandberg R.

Nat Biotechnol. 2016 Dec;34(12):1264-1266. 

Hagemann-Jensen M, Abdullayev I, Sandberg R, Faridani OR.

Nat Protoc. 2018 Oct;13(10):2407-2424.

Larsson AJM, Johnsson P, Hagemann-Jensen M, Hartmanis L, Faridani OR, Reinius B, Segerstolpe Å, Rivera CM, Ren B, Sandberg R.

Nature. 2019 Jan;565(7738):251-254. 

Full publication list in Pubmed



Patents 



People

Omid Faridani , Group Leader


Mehdi Rafeie, Postdoc



Md Imtiazul Islam, Postdoc


Veena Gullapalli, PhD student


Ali Afrasiabi, PhD student


Roger Jiang, Honours student

Alumni:

Nageswara Rao Boggavarapu, Postdoc.

Gurjeet Kaur Virk, Research Assistant

Yun Cheah, Honours student

Collaborators:



Fundings and Awards

Cancer Council NSW 2020 grant 

Single-cell multi-omics of circulating tumour cell clusters.



Contact us


1. UNSW Lowy Cancer Research Centre, Cnr High and Botany St, Kensington  2033 NSW, Australia

2. Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst 2010 NSW, Australia


o.faridani [at] unsw.edu.au 

o.faridani [at] garvan.org.au